Fischl F, Binstorfer E, Reinold E
Wien Med Wochenschr. 1981 Oct 15;131(19):471-4.
Perinatal morbidity and mortality are well known to be higher in macrosomatic neonates, whose birthweight is 4000 g or more. 398 mothers of such macrosomatic infants and 7314 mothers of infants of normal weight were retrospectively reviewed for factors possibly influencing fetal weight. The following items were found to be statistically more frequent or predominant in the study group than in the controls: preconceptional obesity, weight gain of more than 20% during pregnancy, multiparae with an history of macrosomatic infants. Gestation-diabetes (prediabetes) and a family history of diabetes mellitus were observed rarely and did not seem to be of great significance.
众所周知,出生体重4000克及以上的巨大儿围产期发病率和死亡率更高。对398名此类巨大儿的母亲和7314名正常体重婴儿的母亲进行回顾性研究,以寻找可能影响胎儿体重的因素。结果发现,与对照组相比,研究组中以下因素在统计学上更为常见或更为突出:孕前肥胖、孕期体重增加超过20%、有巨大儿生育史的经产妇。妊娠期糖尿病(糖尿病前期)和糖尿病家族史很少见,似乎意义不大。