中枢神经系统两条无髓鞘纤维束的特性：外侧Lissauer束和小脑平行纤维。
Properties of two unmyelinated fibre tracts of the central nervous system: lateral Lissauer tract, and parallel fibres of the cerebellum.
作者信息
Merrill E G, Wall P D, Yaksh T L
出版信息
J Physiol. 1978 Nov;284:127-45. doi: 10.1113/jphysiol.1978.sp012531.
Abstract
- Monoplar tungsten micro-electrodes were used to stimulate and platinun plated tungsten micro-electrodes to record from single, unmyelinated cerebellar parallel fibres and lateral Lissauer tract axons in cats. 2. Stimulation of the lateral Lissauer tract resulted in the activation of a narrow, longitudinal 'beam', much as on the cerebellar surface. 3. Following impulse conduction, parallel and Lissauer tract fibres showed a supernormal conduction velocity (up to 25% increase) and increased excitability (up to 40% increase). No subnormality was encountered following supernormality. Some Lissauer tract fibres had prolonged relative refractory periods and no supernormal periods. 4. Chronaxies ranged from 155 to 380 microseconds. 5. Single fibres exhibited a remarkable increase in conduction velocity (up to 18% and excitability (up to 40%) following a single subthreshold stimulus. The duration of this effect (up to 20 msec) was much longer than expected from membrane time constant estimates.
摘要
- 使用单极钨微电极进行刺激，并使用镀铂钨微电极记录猫的单个无髓小脑平行纤维和外侧脊髓背根 Lissauer 束轴突的活动。2. 刺激外侧脊髓背根 Lissauer 束会导致激活一条狭窄的纵向“束”，这与在小脑表面的情况非常相似。3. 在冲动传导之后，平行纤维和 Lissauer 束纤维表现出超常的传导速度（增加高达 25%）和增加的兴奋性（增加高达 40%）。超常期之后未出现低常期。一些 Lissauer 束纤维具有延长的相对不应期且无超常期。4. 时值范围为 155 至 380 微秒。5. 单个纤维在单次阈下刺激后传导速度显著增加（高达 18%）和兴奋性显著增加（高达 40%）。这种效应的持续时间（长达 20 毫秒）比根据膜时间常数估计预期的要长得多。
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