Cheng Y S, Yeh H C
Am Ind Hyg Assoc J. 1981 Nov;42(11):771-6. doi: 10.1080/15298668191420684.
An aerosol deposition model in the human tracheobronchial tree based on impaction and sedimentation is proposed. Using this model, a mean deposition radius of conducting airways can be obtained from in vivo T-B deposition data or from physical dimensions of human lung casts. Agreement was found between the model and deposition data for three normal healthy subjects in the literature. Contributions of sedimentation to T-B deposition is estimated to be 42 - 78% at 250 cm3/sec average inspiration flow rate, and decreased to 8-29% at 750 cm3/sec average inspiration flow rate. Mean deposition radii are estimated to be 0.33 to 0.43 cm and correlate with pulmonary functional residual capacities.
提出了一种基于撞击和沉降的人体气管支气管树中的气溶胶沉积模型。利用该模型，可以从体内气管支气管沉积数据或人体肺铸型的物理尺寸中获得传导气道的平均沉积半径。文献中发现该模型与三名正常健康受试者的沉积数据之间具有一致性。在平均吸气流量为250立方厘米/秒时，沉降对气管支气管沉积的贡献估计为42%-78%，而在平均吸气流量为750立方厘米/秒时，该贡献降至8%-29%。平均沉积半径估计为0.33至0.43厘米，并与肺功能残气量相关。
