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饮用水中的高钠及其对血压的影响。

High sodium in drinking water and its effect on blood pressure.

作者信息

Hallenbeck W H, Brenniman G R, Anderson R J

出版信息

Am J Epidemiol. 1981 Dec;114(6):817-26. doi: 10.1093/oxfordjournals.aje.a113252.

Abstract

A recent study of two communities in Massachusetts showed that a group of high school sophomores exposed to 107 mg/liter sodium in their municipal drinking water had significantly higher systolic and diastolic blood pressures than a control group exposed to 8 mg/liter. The present study was undertaken to determine if these results could be repeated in two communities, LaGrange and Westchester, located in the Chicago metropolitan area. These communities have similar demographic and socioeconomic characteristics. However, the concentration of sodium in the municipal drinking water of LaGrange is 405 mg/liter as compared to 4 mg/liter for Westchester. A comparison was made between the blood pressures of high school juniors and seniors from the two communities. Of the 386 eligible students in LaGrange, 84% volunteered to have their blood pressures taken. In Westchester, 78% of the 401 eligible students volunteered. Results of the survey indicated that male and female systolic blood pressures in the high sodium community were not significantly higher than those in the low sodium community. Surprisingly, the observed systolic blood pressures of males in the lower sodium community were higher than those in the high sodium community. These findings did not corroborate the results of the Massachusetts study. However, the male and female diastolic blood pressures were significantly higher (p = 0.040 for males and p = 0.016 for females) in the high sodium community. The increases in diastolic blood pressures (approximately 2 mmHg for males and females) were not as large as those observed in the Massachusetts study (2.7 and 5.1 mmHg for males and females, respectively).

摘要

马萨诸塞州两个社区的一项近期研究表明,一组在市政饮用水中接触到每升107毫克钠的高中二年级学生,其收缩压和舒张压显著高于接触每升8毫克钠的对照组。本研究旨在确定这些结果能否在位于芝加哥大都市区的拉格朗日和韦斯特切斯特这两个社区得到重复验证。这些社区具有相似的人口统计学和社会经济特征。然而,拉格朗日市政饮用水中的钠浓度为每升405毫克,而韦斯特切斯特为每升4毫克。对来自这两个社区的高中三年级和四年级学生的血压进行了比较。在拉格朗日的386名符合条件的学生中,84%自愿接受血压测量。在韦斯特切斯特,401名符合条件的学生中有78%自愿参与。调查结果表明,高钠社区的男性和女性收缩压并不显著高于低钠社区。令人惊讶的是,低钠社区男性的收缩压观察值高于高钠社区。这些发现并未证实马萨诸塞州研究的结果。然而,高钠社区的男性和女性舒张压显著更高(男性p = 0.040,女性p = 0.016)。舒张压的升高幅度(男性和女性约为2毫米汞柱)不如马萨诸塞州研究中观察到的幅度大(男性和女性分别为2.7和5.1毫米汞柱)。

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