Lee H R, Wilder R J, Downs P, Massion W, Blank W F
Ann Emerg Med. 1981 Nov;10(11):560-5. doi: 10.1016/s0196-0644(81)80192-8.
Ventricular fibrillation was induced in nine dogs weighing 18 to 22 kg. CPR was performed with a mechanical chest compressor. Mean carotid flow during CPR was 7.9 +/- 1.5 ml/min. After MAST inflation to 100 mm Hg, the flow increased to 15.7 +/- 3.7 ml/min. Intrathoracic aortic systolic pressure was also significantly increased from 65 +/- 7 to 73 +/- 8 mm Hg. When the thorax was vented with chest tubes bilaterally, no change in carotid flow or arterial pressure was noted on closing or opening the chest tubes. One liver laceration and two gallbladder contusions were noted at autopsy. MAST inflation apparently augments carotid flow an systolic pressure. Variations in intrapleural pressure do not seem to have a significant influence on CPR.
在9只体重为18至22千克的狗身上诱发心室颤动。使用机械胸外按压装置进行心肺复苏。心肺复苏期间的平均颈动脉血流量为7.9±1.5毫升/分钟。抗休克裤充气至100毫米汞柱后,血流量增加至15.7±3.7毫升/分钟。胸内主动脉收缩压也从65±7显著升高至73±8毫米汞柱。当通过双侧胸管对胸腔进行排气时,在关闭或打开胸管时未观察到颈动脉血流量或动脉压的变化。尸检时发现一处肝裂伤和两处胆囊挫伤。抗休克裤充气显然可增加颈动脉血流量和收缩压。胸腔内压力的变化似乎对心肺复苏没有显著影响。