Weigand D A, Burgdorf W H, Gregg L J
Arch Dermatol. 1981 Nov;117(11):735-8.
Two patients with discoid lupus erythematosus (DLE) had lesions exhibiting prominent atrophy and telangiectasia. At the time of biopsy, the skin specimens were grossly mucinous. Light and immunofluorescence microscopy findings confirmed the diagnosis of DLE in both cases. Abundant mucin deposition throughout the dermis was also seen microscopically in both cases. Although secondary mucinosis is known to occur in LE, cases with massive mucinous change, ie, those reported herein, have apparently not been recorded. Mucinosis is not considered important in the histologic diagnosis of LE but may create some confusion with other mucinous disorders.
两名盘状红斑狼疮（DLE）患者的皮损表现为明显萎缩和毛细血管扩张。活检时，皮肤标本肉眼观呈黏液样。光镜和免疫荧光显微镜检查结果均确诊为DLE。两例在显微镜下均可见真皮内有大量黏蛋白沉积。虽然已知继发性黏蛋白沉积症可发生于红斑狼疮，但像本文所报道的这种有大量黏液样改变的病例显然尚未见记载。黏蛋白沉积症在红斑狼疮的组织学诊断中并不被认为很重要，但可能会与其他黏液样疾病造成一些混淆。
