Kind P, Goerz G
Universitätshautklinik Düsseldorf.
Z Hautkr. 1987 Sep 15;62(18):1337-8, 1341-2, 1347.
On the basis of LE cases treated at the Department of Dermatology, Düsseldorf University, during the last few years, we present the various forms of cutaneous lupus erythematosus (CLE). 72% of the patients showed discoid lupus erythematosus (DLE), whereas disseminated discoid LE (DDLE) and lupus panniculitis were found in 3% each. Lupus erythematosus tumidus (LET), as well, must be regarded as exceptional. Subacute cutaneous LE (SCLE) and systemic LE (SLE) showed nearly similar frequency (10 and 12%, resp.). Bullous LE is also very rare and must be considered a variant of SLE. The various forms of cutaneous LE can be differentiated according to clinical presentation and histopathology. Direct immunofluorescence, in contrast, has but limited diagnostic value, except with lesions on the scalp. Exact classification of cutaneous LE is the more essential, as it implies considerable therapeutic and prognostic consequences for the patient.
基于过去几年在杜塞尔多夫大学皮肤科治疗的红斑狼疮（LE）病例，我们展示了各种形式的皮肤红斑狼疮（CLE）。72%的患者表现为盘状红斑狼疮（DLE），而播散性盘状LE（DDLE）和狼疮性脂膜炎各占3%。肿胀性红斑狼疮（LET）也被视为罕见情况。亚急性皮肤型LE（SCLE）和系统性LE（SLE）的发生率相近（分别为10%和12%）。大疱性LE也非常罕见，必须被视为SLE的一种变体。各种形式的皮肤LE可根据临床表现和组织病理学进行区分。相比之下，直接免疫荧光除了对头皮病变外，诊断价值有限。皮肤LE的准确分类更为重要，因为这对患者的治疗和预后有重大影响。
