用庆大霉素-聚甲基丙烯酸甲酯珠治疗肾功能受损患者。
Treatment of a patient with impaired renal function with gentamicin-PMMA-beads.
作者信息
Walenkamp G H, Vree T B
出版信息
Arch Orthop Trauma Surg (1978). 1981;99(2):137-41. doi: 10.1007/BF00389749.
PMID:7316706
Abstract
150 gentamicin-PMMA-beads were implanted (+ 160 mg gentamicin i.v. preop.) in a woman aged 73 years and with severely impaired kidney function. Frequent determination of gentamicin plasma concentrations and renal functions were possible. The plasma concentration reached a plateau at approx. 3 micrograms/ml. No accumulation of gentamicin in plasma occurred.
摘要
在一名73岁、肾功能严重受损的女性患者中植入了150颗庆大霉素-聚甲基丙烯酸甲酯珠（术前静脉注射160毫克庆大霉素）。可以频繁测定庆大霉素血浆浓度和肾功能。血浆浓度在约3微克/毫升时达到平台期。血浆中未出现庆大霉素蓄积。
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