Prosser S, Arslan E, Michelini S
Arch Otorhinolaryngol. 1981;233(2):179-87. doi: 10.1007/BF00453642.
The effects of the stimulus repetition rate over the habituated auditory cortical evoked responses were studied. The stimulation pattern consisted of trains of pure tone bursts with interstimulus interval (ISI) of 1 s, and intertrain interval (ITI) of 5 s, delivered with constant time and intensity parameters during 93 min. The analysis of the responses was based upon across averaging of the trains, each single response being evaluated in the latency and amplitude parameters. Two time-dependent factors affected the responses in a distinct way: the habituation throughout the whole stimulation and the rate effect within the train. The linear regressions of the time/amplitude functions of the responses were calculated in relation to the duration of ISI and ITI. By introducing a correction factor depending on the repetition rate it was possible to evaluate the relationships between habituation and repetition rate. Changes in the repetition rate do not have any effect on the habituation process. The two phenomena are completely distinct, and they probably have neurophysiologic substances corresponding to different levels in the central nervous system (CNS).
研究了刺激重复率对习惯化听觉皮层诱发反应的影响。刺激模式由一系列纯音脉冲组成，刺激间隔（ISI）为1秒，系列间隔（ITI）为5秒，在93分钟内以恒定的时间和强度参数进行传递。反应分析基于对系列脉冲的平均，每个单独的反应在潜伏期和幅度参数方面进行评估。两个与时间相关的因素以不同的方式影响反应：整个刺激过程中的习惯化以及系列脉冲内的频率效应。计算了反应的时间/幅度函数相对于ISI和ITI持续时间的线性回归。通过引入一个取决于重复率的校正因子，可以评估习惯化与重复率之间的关系。重复率的变化对习惯化过程没有任何影响。这两种现象完全不同，它们可能具有对应于中枢神经系统（CNS）不同水平的神经生理物质。
