中国仓鼠卵巢细胞中嘌呤和嘧啶代谢的定量分析。
Quantitative analysis of purine and pyrimidine metabolism in Chinese hamster ovary cells.
作者信息
Hunting D, Hordern J, Henderson J F
出版信息
Can J Biochem. 1981 Oct;59(10):838-47. doi: 10.1139/o81-116.
DOI:10.1139/o81-116
PMID:7317815
Abstract
A detailed quantitative study of purine and pyrimidine metabolism in logarithmically growing Chinese hamster ovary cells has been performed. Direct measurements of the ribonucleoside and deoxyribonucleoside triphosphate pool sizes have been made, and the pathways and rates of metabolism of adenine, hypoxanthine, guanine, guanosine, deoxyadenosine, and deoxyguanosine and of uridine, cytidine, deoxycytidine, deoxyuridine, and thymidine have been determined.
摘要
对对数生长期的中国仓鼠卵巢细胞中的嘌呤和嘧啶代谢进行了详细的定量研究。已直接测量了核糖核苷三磷酸和脱氧核糖核苷三磷酸的库大小，并确定了腺嘌呤、次黄嘌呤、鸟嘌呤、鸟苷、脱氧腺苷、脱氧鸟苷以及尿苷、胞苷、脱氧胞苷、脱氧尿苷和胸苷的代谢途径和速率。
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