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一名儿童的严重锂中毒。

Severe lithium intoxication in a child.

作者信息

FitzSimons R B, Keane S

出版信息

Eur J Pediatr. 1981 Nov;137(3):353-4. doi: 10.1007/BF00443272.

DOI:10.1007/BF00443272
PMID:7318849
Abstract

A mentally retarded six-year-old child became severely intoxicated with lithium carbonate whilst on maintenance lithio-therapy for control of aggressive behaviour in an institutional setting. His lithium level of 5.15 mmol/l returned to normal after two weeks. Treatment consisted of an initial saline infusion but was otherwise supportive. Although lithium toxicity is rare in children this may be because it had been used infrequently and cautiously. We feel his young age and situation accounted for some of the severity of his intoxication, and wish to stress the potential toxicity of lithium when used under these circumstances.

摘要

一名六岁的智障儿童在机构环境中接受碳酸锂维持治疗以控制攻击性行为时,发生了严重的碳酸锂中毒。他的锂水平为5.15毫摩尔/升,两周后恢复正常。治疗包括最初的生理盐水输注,其他则为支持性治疗。尽管儿童锂中毒很少见,但这可能是因为其使用频率低且谨慎。我们认为他的年幼和所处环境是其中毒严重程度的部分原因,并希望强调在这些情况下使用锂时的潜在毒性。

相似文献

1
Severe lithium intoxication in a child.一名儿童的严重锂中毒。
Eur J Pediatr. 1981 Nov;137(3):353-4. doi: 10.1007/BF00443272.
2
The management of chronic behavior disorders in mentally retarded adults with lithium carbonate.碳酸锂对成年智障者慢性行为障碍的治疗
J Nerv Ment Dis. 1981 Mar;169(3):191-5. doi: 10.1097/00005053-198103000-00007.
3
Lithium carbonate in the management of hyperactive aggressive behavior of the mentally retarded.
Compr Psychiatry. 1977 Nov-Dec;18(6):599-606. doi: 10.1016/s0010-440x(97)90013-4.
4
Lithium treatment and cognitive changes in two mentally retarded patients.
J Nerv Ment Dis. 1986 Nov;174(11):689-92. doi: 10.1097/00005053-198611000-00008.
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[Lithium intoxication in a patient with severe motor and intellectual disabilities].[一名患有严重运动和智力残疾患者的锂中毒]
No To Hattatsu. 2003 Sep;35(5):422-5.
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Lithium carbonate for aggression in mentally retarded persons.碳酸锂治疗智力迟钝者的攻击行为。
Compr Psychiatry. 1989 Nov-Dec;30(6):505-11. doi: 10.1016/0010-440x(89)90080-1.
7
Lithium in the treatment of aggression in mentally handicapped patients. A double-blind trial.锂盐治疗智障患者的攻击行为。一项双盲试验。
Br J Psychiatry. 1987 May;150:685-9. doi: 10.1192/bjp.150.5.685.
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Lithium therapy in aggressive mentally subnormal patients.对有攻击性的轻度精神发育迟滞患者进行锂盐治疗。
Br J Psychiatry. 1980 Nov;137:469-74. doi: 10.1192/bjp.137.5.469.
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Factors associated with a good response to lithium in aggressive mentally handicapped subjects.与有攻击行为的智力障碍患者对锂盐良好反应相关的因素。
Prog Neuropsychopharmacol Biol Psychiatry. 1984;8(4-6):751-5. doi: 10.1016/0278-5846(84)90052-6.
10
Acute lithium intoxication.急性锂中毒
Anaesth Intensive Care. 2002 Feb;30(1):90-2. doi: 10.1177/0310057X0203000118.

本文引用的文献

1
The effect of lithium carbonate on leukopenia after chemotherapy.碳酸锂对化疗后白细胞减少症的影响。
J Pediatr. 1980 May;96(5):923-7. doi: 10.1016/s0022-3476(80)80583-x.
2
Hyperosmolality complicating recovery from lithium toxicity.高渗血症使锂中毒恢复过程复杂化。
Br Med J. 1978 Jun 10;1(6126):1522-3. doi: 10.1136/bmj.1.6126.1522.
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Side effects associated with lithium therapy.
Arch Gen Psychiatry. 1979 Jul 20;36(8 Spec No):879-87. doi: 10.1001/archpsyc.1979.01780080053013.
4
Manic states in affective disorders of childhood and adolescence.儿童及青少年情感障碍中的躁狂状态。
Br Med J. 1979 Mar 10;1(6164):685. doi: 10.1136/bmj.1.6164.685.
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Lithium in child and adolescent psychiatry.
Arch Gen Psychiatry. 1979 Jul 20;36(8 Spec No):854-5. doi: 10.1001/archpsyc.1979.01780080028008.
6
Lithium intoxication. (Report of 23 cases and review of 100 cases from the literature).锂中毒。(23例报告及文献中100例回顾)
Q J Med. 1978 Apr;47(186):123-44.