Heim M, Ganel A, Horoszowski H, Farine I
J Trauma. 1981 Dec;21(12):1050-1. doi: 10.1097/00005373-198112000-00010.
Factor XI (PTA) deficiency, a coagulopathy, has been found to be relatively common in Ashkenazi Jews. Clinically it may manifest itself by varying forms of hemorrhage including postoperative bleeding. It is recommended that all Ashkenazi Jews have a partial thromboplastin time (PTT) coagulation test before surgery in order to rule out this coagulopathy, and if the PTT is abnormal a Factor XI assay should be done to confirm the diagnosis and ensure that proper therapy can be provided. A surgical case is presented with its ensuing complications resulting form lack of such information.
凝血因子XI（PTA）缺乏症是一种凝血病，在德系犹太人中相对常见。临床上，它可能表现为各种形式的出血，包括术后出血。建议所有德系犹太人在手术前进行部分凝血活酶时间（PTT）凝血试验，以排除这种凝血病，如果PTT异常，应进行凝血因子XI测定以确诊，并确保能提供适当的治疗。本文介绍了一个因缺乏此类信息而引发并发症的手术病例。
