de Sieyes D C, Douple E B, Strohbehn J W, Trembly B S
Med Phys. 1981 Mar-Apr;8(2):174-83. doi: 10.1118/1.594930.
Hyperthermia has emerged as a promising alternative or adjunct to other forms of cancer therapy. In order to utilize hyperthermia in very localized volumes immersed in regions of vital normal tissue, an invasive microwave coaxial monopole antenna has been developed. An experimental approach has been taken to characterize and optimize the electromagnetic properties and heating capabilities of bare and insulated antennas imbedded in tissue equivalent phantoms and dog brain. Four methods have been used to visualize the thermal profiles of the microwave probes: the liquid crystal technique, the gelatin technique, and the direct measurement of temperature with thermistor probes in phantom and dog brain. Among the parameters studied are: antenna impedance, insertion depth, antenna insulation (dielectric constant and thickness), shaft insulation, and frequency.
热疗已成为一种有前景的替代疗法或其他癌症治疗形式的辅助疗法。为了在浸没于重要正常组织区域的非常局部的体积中利用热疗，已开发出一种侵入性微波同轴单极天线。已采用一种实验方法来表征和优化嵌入组织等效体模和狗脑内的裸天线和绝缘天线的电磁特性及加热能力。已使用四种方法来可视化微波探头的热分布：液晶技术、明胶技术以及用热敏电阻探头在体模和狗脑中直接测量温度。所研究的参数包括：天线阻抗、插入深度、天线绝缘（介电常数和厚度）、轴绝缘以及频率。
