Linnane J W, Burry A F, Emmerson B T
Nephron. 1981;29(5-6):216-22. doi: 10.1159/000182373.
Urate deposits within microtophi were found in 8% of unselected autopsies in Brisbane, Australia. Significant association were demonstrated with (a) a history of gouty arthritis and (b) the existence of nitrogen retention and renal disease of apparently primary, but not gouty, origin. However, in 26% of the patients, a retrospective survey of their medical records did not reveal any causative factor. The possible aetiological importance of the urine flow rate is stressed. The presence of medullary urate deposits at autopsy was most frequently associated with a history of gout or the presence of pre-existing and non-gouty renal disease, although no aetiological factor could be determined in a quarter of the cases.
在澳大利亚布里斯班，对未经挑选的尸体解剖进行检查发现，8%的病例存在微痛风石内尿酸盐沉积。研究表明，这与以下因素存在显著关联：（a）痛风性关节炎病史；（b）存在氮潴留以及明显原发性而非痛风性起源的肾脏疾病。然而，在26%的患者中，对其病历进行回顾性调查未发现任何致病因素。文中强调了尿流率在病因学上可能具有的重要性。尸检时发现髓质尿酸盐沉积最常与痛风病史或先前存在的非痛风性肾脏疾病有关，尽管在四分之一的病例中无法确定病因。
