Mauguiere F, Bard J, Courjon J
Rev Electroencephalogr Neurophysiol Clin. 1981 Nov;11(2):174-82. doi: 10.1016/s0370-4475(81)80050-0.
Short-latency SEPs following stimulation of the median nerve at the wrist have been studied in 6 patients suffering from dyssynergia cerebellaris myoclonica (DCM). Cervical N14 and scalp-recorded P15 potentials were found to be normal in patients with appropriate recording conditions. The N20 potential, usually recorded in normals in the parietal region contralateral to the stimulated side, was recorded only in 3 cases out of 6. When present, the N20 potential was found to be normal in latency, amplitude and topography. These data suggest that the electrophysiological events related with information processing at the subcortical levels of the lemniscal pathways (N14, P15) are unmodified in DCM, and lend substance to the hypothesis of a cortical long-loop reflex responsible for the triggering of intention myoclonus in these patients.
对6例患有肌阵挛性小脑协同失调（DCM）的患者进行了研究，刺激其腕部正中神经后的短潜伏期体感诱发电位。在记录条件合适的患者中，发现颈段N14和头皮记录的P15电位正常。通常在正常人受刺激侧对侧顶叶区域记录到的N20电位，在6例中仅3例记录到。当出现N20电位时，其潜伏期、波幅和地形图均正常。这些数据表明，在DCM中，与感觉传导通路皮质下水平信息处理相关的电生理事件未改变，支持了皮质长环反射假说，该假说认为这种反射是这些患者意向性肌阵挛触发的原因。
