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无症状潜水员的血细胞变化

Blood cell changes in asymptomatic divers.

作者信息

Barnard E E, Weathersby P K

出版信息

Undersea Biomed Res. 1981 Dec;8(4):187-98.

PMID:7324252
Abstract

Many recent reports have suggested that diving and decompression cause changes in blood cells even when no overt symptoms of decompression sickness are present. This study subjected 10 normal persons to a pressure exposure of 100 fsw (30.5 msw) for 60 min followed by the standard U.S. Navy decompression schedule. No subject had symptoms of clinical decompression sickness. Repeated blood samples over a 3-week period spanning the simulated dive were analyzed for numbers of red cells, white cells, reticulocytes, platelets (by three methods), and size distribution of platelets. The study was designed to detect postdive changes of less than 5%. Small but definite decreases were found in levels of red cells, white cells, hematocrit, and platelets (by microscopic methods but not by machine), and the proportion of large platelets rose. The changes were too mild to support a proposed mechanism of decompression damage.

摘要

许多近期报告表明,即使没有明显的减压病症状,潜水和减压也会导致血细胞发生变化。本研究让10名正常人在100英尺海水深度(30.5米海水深度)下暴露60分钟,然后按照美国海军标准减压方案进行减压。没有受试者出现临床减压病症状。在模拟潜水后的3周内,对重复采集的血样进行分析,检测红细胞、白细胞、网织红细胞、血小板数量(采用三种方法)以及血小板大小分布。该研究旨在检测潜水后小于5%的变化。结果发现红细胞、白细胞、血细胞比容和血小板水平(通过显微镜检查法而非机器检测法)出现了虽小但明确的下降,并且大血小板比例上升。这些变化过于轻微,无法支持所提出的减压损伤机制。

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