饱和潜水期间血小板计数下降。

Decrease in platelet count during saturation diving.

作者信息

Domoto H, Nakabayashi K, Hashimoto A, Suzuki S, Kitamura T

机构信息

Japan Maritime Self-Defense Force Undersea Medical Center, Yokosuka, Kanagawa.

出版信息

Aviat Space Environ Med. 2001 Apr;72(4):380-4.

PMID:11318019

Abstract

BACKGROUND

The change in platelet count (PC) occurring during saturation diving has rarely been discussed. We set out to clarify the details of this change in PC, and its relationship with: i) the storage depth and duration of the saturation dive, and ii) the presence of decompression bubbles.

METHODS

In a total of 42 divers, the change in PC was measured in 8 simulated saturation dives (1992-1998) using a Deep Diving Simulator with decompression procedures based on the modified DUKE-GKSS schedule. Blood samples were taken before the dive, at the bottom (twice), during decompression, on surfacing, and about 1 wk after surfacing. Decompression bubbles were examined by ultrasonic M-mode echocardiography.

RESULTS

PC (mean +/- SD x 10(4) x microl(-1)) was 23.9 +/- 4.85, 24.9 +/- 4.9, 24.2 +/- 4.8, 19.2 +/- 4.4*, 20.1 +/- 4.5*, 25.0 +/- 5.1 on the occasions listed above (*= p < 0.05 vs. pre-dive). The PC showed no correlation with either storage depth or dive duration. Decompression bubbles were detected during decompression in only 2 divers (4.8%), and the bubbles disappeared immediately after surfacing. In these 2 divers the decreases in PC values from baseline to the middle of decompression and on surfacing were 2 and 2.7 x 10(4) x microl(-1), and 3.4 and 1.7 x 10(4) x microl(-1) respectively. No diver complained of decompression sickness.

CONCLUSION

The magnitude of the decrease in PC (< 5 x 10(4) x microl(-1)) and the time to recover to the pre-dive value (< 1 wk) suggests that changes in PC during saturation diving should not cause any clinical problems. The mechanisms underlying the decrease in PC remain unclear.

摘要

背景

关于饱和潜水过程中血小板计数（PC）的变化鲜有讨论。我们旨在阐明PC这种变化的细节，以及它与以下因素的关系：i）饱和潜水的储存深度和持续时间，ii）减压气泡的存在情况。

方法

在总共42名潜水员中，于1992年至1998年期间使用深度潜水模拟器进行了8次模拟饱和潜水，采用基于改良的DUKE - GKSS方案的减压程序，测量PC的变化。在潜水前、水底（两次）、减压期间、浮出水面时以及浮出水面后约1周采集血样。通过超声M型心动图检查减压气泡。

结果

上述各时间点的PC（平均值±标准差×10⁴×μl⁻¹）分别为23.9±4.85、24.9±4.9、24.2±4.8、19.2±4.4*、20.1±4.5*、25.0±5.1（*表示与潜水前相比，p<0.05）。PC与储存深度或潜水持续时间均无相关性。仅在2名潜水员（4.8%）的减压过程中检测到减压气泡，气泡在浮出水面后立即消失。在这2名潜水员中，从基线到减压中期以及浮出水面时PC值的下降分别为2和2.7×10⁴×μl⁻¹，以及3.4和1.7×10⁴×μl⁻¹。没有潜水员抱怨患减压病。