Buletsa B A, Buletsa V I, Pashchenko A E, Megela R M, Korshinskiĭ I Iu
Zh Nevropatol Psikhiatr Im S S Korsakova. 1981;81(9):1301-4.
Experiments on 30 rabbits, as well as clinical studies on 180 patients with cerebral circulation disorders were carried out. It was found that in patients with hypertensive disease complication, thyroid hyperactivity was observed only in the age group of 35 to 45 years. It was also found that in the patients with hypertensive disease and the complications of the latter, repeated stresses intensified the neurosecretory functions of the hypophysis and the hypothalamus: this, in its turn, influenced the hormone-synthetizing function of the thyroid. The chronic hyperthyroid syndrome present in those patients led to an increased oxygen consumption by tissues, slowed down the electron transport along the respiratory chain, increased the content of iodine and protein, and intensified the effects of pressor agents, i. e. aggravated the symptoms of the hypertensive disease. All those factors play a definite role in the mechanism of the development of the cerebral circulation disorders in hypertensive patients.
对30只兔子进行了实验，并对180名脑循环障碍患者进行了临床研究。结果发现，在高血压病并发症患者中，仅在35至45岁年龄组观察到甲状腺功能亢进。还发现，在患有高血压病及其并发症的患者中，反复应激会增强垂体和下丘脑的神经分泌功能：这进而影响甲状腺的激素合成功能。这些患者中存在的慢性甲状腺功能亢进综合征导致组织耗氧量增加、呼吸链上的电子传递减慢、碘和蛋白质含量增加，并增强了升压剂的作用，即加重了高血压病的症状。所有这些因素在高血压患者脑循环障碍的发生机制中都起一定作用。
