Maheshwari M C, Padmini R
Acta Neurol Scand. 1981 Jul;64(1):22-8. doi: 10.1111/j.1600-0404.1981.tb04382.x.
Carbamazepine was given to 152 patients who were receiving multiple drug therapy for uncontrolled seizures. The age range was 3 to 57 years. The mean average duration of epilepsy and carbamazepine therapy was 7.6 years and 19 months respectively. The conclusions are: (i) Carbamazepine is effective in reducing the multiple drug therapy while still maintaining better control of epilepsy. (ii) Carbamazepine by reducing polypharmacy in epilepsy and probably by the relative lack of sedative action is effective in improving school or work performances. (iii) Carbamazepine is a safe antiepileptic drug.
对152例接受多种药物治疗但癫痫仍未得到控制的患者给予卡马西平。年龄范围为3至57岁。癫痫和卡马西平治疗的平均持续时间分别为7.6年和19个月。结论如下：（i）卡马西平在减少多种药物治疗的同时，仍能更好地控制癫痫。（ii）卡马西平通过减少癫痫的联合用药，可能还因其相对缺乏镇静作用，对改善学习或工作表现有效。（iii）卡马西平是一种安全的抗癫痫药物。
