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母亲及其新生儿的血液农药浓度。与早产的关系。

Blood pesticide concentration in mothers and their newborn infants. Relation to prematurity.

作者信息

Procianoy R S, Schvartsman S

出版信息

Acta Paediatr Scand. 1981 Nov;70(6):925-8. doi: 10.1111/j.1651-2227.1981.tb06252.x.

DOI:10.1111/j.1651-2227.1981.tb06252.x
PMID:7324948
Abstract

An association between high DDT cord blood levels and prematurity was investigated. Pregnant women with good health and nutritional condition, negative history of past occupational exposure to DDT and absence of recent exposure to DDT were investigated as well as their appropriate for gestational age neonates. A total of 54 maternal-infant pairs were studied and divided in two groups: A-term deliveries (30 pairs), B-preterm deliveries (24 pairs). There was no difference in DDT blood levels between pregnant women of both groups. There was, however, a significant difference in DDT cord blood levels between term and preterm infants, as well as between maternal and neonatal blood levels in both groups. DDT cord blood levels correlated negatively with infants' birth weights. We suggest that there is an association between prematurity and high DDT cord blood levels in a non-occupationally exposed population and the amount of fetal adipose tissue is an important factor determining the cord blood level of this pesticide. We cannot rule out a cause-effect association between high DDT cord blood level and prematurity.

摘要

对高滴滴涕脐带血水平与早产之间的关联进行了调查。对健康状况和营养状况良好、既往无职业性滴滴涕接触史且近期无滴滴涕接触史的孕妇及其孕周合适的新生儿进行了调查。共研究了54对母婴,并将其分为两组:A组为足月分娩(30对),B组为早产分娩(24对)。两组孕妇的滴滴涕血水平无差异。然而,足月和早产婴儿的脐带血滴滴涕水平之间以及两组孕妇和新生儿的血水平之间存在显著差异。脐带血滴滴涕水平与婴儿出生体重呈负相关。我们认为,在非职业暴露人群中,早产与高脐带血滴滴涕水平之间存在关联,胎儿脂肪组织的量是决定这种农药脐带血水平的重要因素。我们不能排除高脐带血滴滴涕水平与早产之间的因果关联。

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