Niessen K H, Ramolla J, Binder M, Brügmann G, Hofmann U
Eur J Pediatr. 1984 Sep;142(4):238-44. doi: 10.1007/BF00540242.
Chlorinated hydrocarbon and polychlorinated biphenyl (PCB) concentrations were determined in adipose tissue from 34 infants, 14 children in the 2nd year of life, and 2 older children. The highest mean concentration detected during the first 2 years of life was for PCBs (0.67 ppm), followed by DDT (0.57 ppm), HCB (0.23 ppm), and HCH (0.15 ppm). Concentrations of HCB and PCB, which are especially characteristic of highly industrialised countries, were considerably higher in children of German mothers than in those of Turkish mothers. All single investigated values were lower than the mean values for adults in the Federal Republic of Germany, but many were still higher than mean concentrations for adults in other parts of the world. A breakdown into children with high mothers' milk intake and those with low intake showed a highly significant association with the quantity of mothers' milk consumed: the concentration of organohalogens in adipose tissue of children with high intake was significantly higher than in those with low intake. Two tasks urgently demand our attention: the development of further ways to reduce environmental sources of organohalogen contamination and the study of the possible pathogenetic effect of these organohalogens on the health of our children.
测定了34名婴儿、14名2岁儿童和2名大龄儿童脂肪组织中的氯代烃和多氯联苯（PCB）浓度。生命最初2年检测到的平均浓度最高的是多氯联苯（0.67 ppm），其次是滴滴涕（0.57 ppm）、六氯苯（0.23 ppm）和六氯环己烷（0.15 ppm）。六氯苯和多氯联苯的浓度是高度工业化国家的典型特征，德国母亲的孩子体内这些物质的浓度明显高于土耳其母亲的孩子。所有单个检测值均低于德意志联邦共和国成年人的平均值，但许多仍高于世界其他地区成年人的平均浓度。将儿童分为母乳摄入量高和摄入量低两组后发现，这与母乳摄入量有高度显著的关联：摄入量高的儿童脂肪组织中有机卤素的浓度明显高于摄入量低的儿童。有两项任务迫切需要我们关注：开发更多减少有机卤素环境污染源的方法，以及研究这些有机卤素对我们孩子健康可能产生的致病作用。
