Carpenter R J, Banks P M, McDonald T J, Sanderson D R
Laryngoscope. 1978 Dec;88(12):1963-9. doi: 10.1288/00005537-197812000-00011.
The term "sinus histiocytosis with massive lymphadenopathy," introduced in 1969 by Rosai and Dorfman, refers to a newly recognized disease entity characterized by painless cervical lymphadenopathy, fever, leukocytosis, increased erythrocyte sedimentation rate, and hypergammaglobulinemia. The typical course is one of insidious onset, protracted duration of the active disease state, and eventual spontaneous remission, occasionally with subsequent recurrences. Lymph nodes other than those in the cervical area may be involved, and extranodal involvement can occur (such as in the orbit, skin, or respiratory tract). Clinically, this entity may closely simulate malignant lymphoma or nonneoplastic conditions with lymphadenopathy. We present a case in which this disease process extensively involved the respiratory tract and produced obstructive symptoms. The otorhinolaryngologist should be aware of this disease entity and should include it in the differential diagnosis for patients with cervical lymph node enlargement or bronchial obstruction.
“伴有巨大淋巴结病的窦组织细胞增生症”这一术语由罗萨伊和多尔夫曼于1969年提出，指的是一种新认识的疾病实体，其特征为无痛性颈部淋巴结病、发热、白细胞增多、红细胞沉降率升高和高球蛋白血症。典型病程为起病隐匿，疾病活动状态持续时间长，最终自发缓解，偶尔会复发。除颈部淋巴结外，其他部位的淋巴结也可能受累，并且可发生结外受累（如眼眶、皮肤或呼吸道）。临床上，该实体可能与恶性淋巴瘤或伴有淋巴结病的非肿瘤性疾病极为相似。我们报告一例该疾病过程广泛累及呼吸道并产生阻塞症状的病例。耳鼻喉科医生应了解这一疾病实体，并应将其纳入颈部淋巴结肿大或支气管阻塞患者的鉴别诊断中。
