Helms C M, Lengeling R W, Pinsky R L, Myers M G, Koontz F P, Klassen L W, Wintermeyer L A
Am J Med Sci. 1981 Sep-Oct;282(2):50-60. doi: 10.1097/00000441-198109000-00001.
We reviewed retrospectively the clinical records of 25 women ages 13 to 41 years who had diagnosed illnesses compatible wtih toxic shock syndrome (TSS). Cases occurred between January 1976 and October 1980. Fourteen confirmed TSS cases and 11 probable TSS cases were identified. In each case initial symptoms occurred in association with menstrual bleeding and tampon use. All patients were febrile. Hypotension occurred in 20 cases, but five patients with milder illness remained normotensive. An erythematous rash occurred in 20 cases. Desquamation occurred in convalescence in all but two cases. Complications included delirium or coma, acute renal failure, and respiratory distress syndrome. Thirteen patients had recurrences of TSS. S. aureus was isolated from the vagina or cervix in 75% of cases. There is a spectrum of severity associated with TSS. Strict diagnostic criteria established heretofore for epidemiologic studies of TSS may not be met by all cases of TSS.
我们回顾性地查阅了25名年龄在13至41岁之间、被诊断患有与中毒性休克综合征（TSS）相符疾病的女性的临床记录。病例发生在1976年1月至1980年10月之间。确定了14例确诊的TSS病例和11例可能的TSS病例。在每例病例中，初始症状均与月经出血和使用卫生棉条有关。所有患者均发热。20例出现低血压，但5例病情较轻的患者血压正常。20例出现红斑皮疹。除两例外，所有患者在恢复期均出现脱皮。并发症包括谵妄或昏迷、急性肾衰竭和呼吸窘迫综合征。13例患者TSS复发。75%的病例从阴道或宫颈分离出金黄色葡萄球菌。TSS存在一系列严重程度。此前为TSS流行病学研究制定的严格诊断标准可能并非所有TSS病例都能满足。
