血清中抗菌剂检测的厌氧平板法。
Anaerobic plate method for assaying antimicrobial agents in serum.
作者信息
Smith J A, Ngui-Yen J H
出版信息
Antimicrob Agents Chemother. 1981 Nov;20(5):678-80. doi: 10.1128/AAC.20.5.678.
Abstract
An anaerobic agar plate method was devised for the assay of antimicrobial agents in serum by using a strain of Clostridium bifermentans. The method gave reproducible and accurate in assays of chloramphenicol, clindamycin, and metronidazole alone or in the presence of beta-lactam or aminoglycoside antibiotics.
摘要
设计了一种厌氧琼脂平板法，通过使用双发酵梭菌菌株来测定血清中的抗菌剂。该方法在单独测定氯霉素、克林霉素和甲硝唑或在存在β-内酰胺或氨基糖苷类抗生素的情况下进行测定时，结果具有可重复性和准确性。
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本文引用的文献
1
Microbiological agar diffusion assay for metronidazole concentrations in serum.血清中甲硝唑浓度的微生物琼脂扩散测定法。
Antimicrob Agents Chemother. 1974 May;5(5):466-8. doi: 10.1128/AAC.5.5.466.
2
Simple assay for clindamycin in the presence of aminoglycosides.在氨基糖苷类药物存在的情况下对克林霉素进行的简易检测
Antimicrob Agents Chemother. 1974 Dec;6(6):831-5. doi: 10.1128/AAC.6.6.831.
3
Bioassay of metronidazole with either anaerobic or aerobic incubation.
J Infect Dis. 1975 Nov;132(5):587-91. doi: 10.1093/infdis/132.5.587.
4
Rapid bioassay for clindamycin alone and in the presence of aminoglycoside antibiotics.单独及在氨基糖苷类抗生素存在情况下对克林霉素的快速生物测定。
J Infect Dis. 1977 Sep;136(3):422-7. doi: 10.1093/infdis/136.3.422.
5
Chloramphenicol bioassay.氯霉素生物测定法。
Antimicrob Agents Chemother. 1979 Jul;16(1):43-5. doi: 10.1128/AAC.16.1.43.
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