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[一名2岁男孩的膀胱横纹肌肉瘤]

[Rhabdomyosarcoma of the bladder in a 2-year-old boy].

作者信息

Otvagina G A, Evdokimov V N

出版信息

Arkh Patol. 1981;43(12):57-9.

PMID:7325825
Abstract

A case of rarely occurring rhabdomyosarcoma of the urinary bladder in a boy of 2 is presented. The period from the first clinical manifestations (pyuria, macrohematuria) to death was 4 months. Urological examinations were done at the period of manifest clinical signs of disuria. A tumour of the urinary bladder almost completely filling the lumen was found in the form of numerous papillary-polyplike formations, with uropassage disorders. On the materials of operation biopsy the histological conclusion of urinary bladder rhabdomyosarcoma was reached. The death occurred with urogenic infection and manifestations of drug agranulocytosis (cytostatic therapy). The tumour outgrew into the posterior wall, no metastases were found. Histologically the tumour was characterized by random arrangement of mono- and multinuclear polymorphic cells with oxiphilic cytoplasm. The granularity and fibrous pattern of the cytoplasm were discernible. Typically, an argirophilic framework was observed. By its histological structure the tumour belongs to the embryonal type.

摘要

本文报告一例2岁男孩罕见的膀胱横纹肌肉瘤病例。从首次临床表现(脓尿、肉眼血尿)至死亡历时4个月。在出现排尿困难的明显临床症状期间进行了泌尿外科检查。发现膀胱肿瘤几乎完全充满管腔,呈大量乳头状-息肉样结构,伴有尿路梗阻。根据手术活检材料得出膀胱横纹肌肉瘤的组织学诊断。患者死于泌尿生殖系统感染和药物性粒细胞缺乏症(细胞抑制疗法)表现。肿瘤向后壁生长,未发现转移。组织学上,肿瘤的特征是单核和多核多形细胞随机排列,细胞质嗜酸性。细胞质的颗粒状和纤维状形态清晰可见。通常可见嗜银纤维框架。根据其组织结构,该肿瘤属于胚胎型。

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