Cetina Sauri G, Larracilla Alegre J, Palacios de Colón D
Bol Med Hosp Infant Mex. 1981 Sep-Oct;38(5):763-70.
The literature on serum lysozyme was reviewed and the normal values for this enzyme were analyzed in 40 healthy children (control group) and 40 children with a clinical diagnosis of septicemia. The patients were 1 to 18 months old and were hospitalized in the H.P. of the C.M.N., I.M.S.S. In 12 of these, the blood cultures developed bacteria, while 26 were negative. It was found that the normal values varied in healthy children from 5 to 24 microgram/ml. In the group of infected patients, the values varied from 4.4 to 53.3 microgram/ml. The group of healthy patients (control) was compared with the infected patients and a significantly difference was found (p less than 0.05), although in some infected children the readings for lysozyme were normal. In all patients, lysozyme returned to normal when the infection cleared. The mortality rate in this study was 15 per cent. It is concluded that in patients with severe infection, the levels of lysozyme in the serum may the elevated, while in patients with clinical signs of septicemia with positive blood cultures, there is a rise in lysozyme.
对血清溶菌酶的文献进行了综述，并分析了40名健康儿童（对照组）和40名临床诊断为败血症的儿童的该酶正常值。患者年龄在1至18个月之间，在墨西哥社会保险局医学中心综合医院住院。其中12例血培养培养出细菌，26例为阴性。结果发现，健康儿童的正常值在5至24微克/毫升之间。在感染患者组中，数值在4.4至53.3微克/毫升之间。将健康患者组（对照组）与感染患者进行比较，发现有显著差异（p小于0.05），尽管一些感染儿童的溶菌酶读数正常。在所有患者中，感染清除后溶菌酶恢复正常。本研究中的死亡率为15%。结论是，在严重感染患者中，血清溶菌酶水平可能升高，而在血培养阳性的败血症临床体征患者中，溶菌酶会升高。
