Longstreth G F, Slivka J
J Clin Gastroenterol. 1981;3 Suppl 1:47-50. doi: 10.1097/00004836-198100031-00010.
Oral cholecystography (OCG) has traditionally been delayed until several weeks after hospitalization for pancreatitis because of the putative frequent poor visualization during the acute episode. Recently, OCG with iopanoic acid was reported successful in most patients with acute pancreatitis soon after resumption of a solid diet. We evaluated OCG with sodium tyropanoate, a pharmacokinetically different contrast material, in 30 hospitalized patients with pancreatitis before resumption of solid food. It accurately evaluated the gallbladder in 24 cases (80%). Abnormal liver function tests, including mild hyperbilirubinemia, did not interfere with the examination. Consequently, 1) tyropanoate OCG adequately opacifies the gallbladder in most patients with acute pancreatitis who are fasting or taking liquids only; 2) allows gallbladder evaluation earlier than with iopanoic acid OCG; 3) is less affected by hepatic dysfunction; and 4) provides an alternative to ultrasonography.
传统上，口服胆囊造影术（OCG）会推迟到胰腺炎患者住院几周后进行，因为在急性发作期间，推测其显影效果常常不佳。最近，有报道称，在大多数急性胰腺炎患者恢复固体饮食后不久，使用碘番酸进行口服胆囊造影术取得了成功。我们对30例住院胰腺炎患者在恢复固体食物前使用苯丙酸钠（一种药代动力学不同的造影剂）进行了口服胆囊造影术评估。它在24例（80%）患者中准确评估了胆囊。包括轻度高胆红素血症在内的肝功能异常检查并未干扰检查。因此，1）苯丙酸钠口服胆囊造影术能使大多数禁食或仅进食流食的急性胰腺炎患者的胆囊充分显影；2）比碘番酸口服胆囊造影术能更早地对胆囊进行评估；3）受肝功能障碍的影响较小；4）可作为超声检查的替代方法。
