放射治疗后软组织中99mTc二膦酸盐活性的消失。
Disappearance of soft tissue 99mTc diphosphonate activity following radiation therapy.
作者信息
Hill L T
出版信息
J Natl Med Assoc. 1981 Dec;73(12):1119-21.
The appearance of soft tissue concentrations of technitium labeled phosphate compounds has been observed in a variety of pathological conditions. The mechanism and pathophysiology of this phenomenon remain unclear.Seven new patients diagnosed with lung cancer received (99m)Tc diphosphonate bone scans during the period of January 1975 to November 1975. Three of the seven subjects showed a significant accumulation of isotope in the region of the chest infiltrate at the time of diagnosis. Upon repeat technitium bone scans six months post radiation, two patients showed a sharp reduction in the soft tissue activity previously observed.The material is presented and a possible explanation of this phenomenon is offered.
在多种病理情况下，均观察到了锝标记的磷酸盐化合物在软组织中的聚集现象。该现象的机制和病理生理学仍不清楚。1975年1月至1975年11月期间，7名新诊断为肺癌的患者接受了（99m）锝二膦酸盐骨扫描。7名受试者中有3名在诊断时胸部浸润区域出现了明显的同位素聚集。放疗后6个月重复进行锝骨扫描时，2名患者先前观察到的软组织活性急剧降低。本文展示了相关材料，并对这一现象给出了一种可能的解释。
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