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颅内转移瘤的假性血管综合征(作者译)

[The pseudo-vascular syndrome of intracrânial metastases (author's transl)].

作者信息

de Divitiis E, Spaziante R, Stella L, Donzelli R

出版信息

Neurochirurgie. 1978;24(4):235-8.

PMID:732923
Abstract

Our statistic consist of 162 cases of metastatic tumors of the brain (M.T.B.), of which 120 verified under surgery or at autopsy, and 42 diagnosed in the pre-operative phase and not undergone surgery. The pseudo-vascular form has been found in 58 cases (36%). If we only consider the supratentorial localizations, this percentage rises to 43,5%. This onset of symptomatology is quite predominant in males (52 cases 42%) compared to females (6 cases: 16%). The MTBs that in our statistics produce a greater frequence of pseudo-vascular forms are the MTBs of melanomas (66%), those of unknown origin (42%) and those of pulmonary origin (35%). These neoplasms are distinctly more frequent in males. On the contrary the mammary metastases responsible for most of the female MTBs originate to a pseudo-vascular form in only 22% of the cases. The etio-pathogenetic mechanism is double; it may be the manifestation either of arterial occlusion by neoplastic cells (embolia neoplastica attiva) or of disruption of the vascular wall and hemorrhage. As far as the diagnosis is concerned this syndrome can be quite easily recognised only when an extraneuraxial tumor is found, especially with a marked neuraxial tropism.

摘要

我们的统计数据包括162例脑转移瘤(M.T.B.),其中120例经手术或尸检证实,42例在术前阶段诊断但未接受手术。假血管型在58例(36%)中被发现。如果仅考虑幕上定位,这一百分比升至43.5%。与女性(6例:16%)相比,这种症状的发作在男性中更为常见(52例:42%)。在我们的统计中,产生假血管型频率较高的脑转移瘤是黑色素瘤脑转移瘤(66%)、不明来源脑转移瘤(42%)和肺源性脑转移瘤(35%)。这些肿瘤在男性中明显更为常见。相反,导致大多数女性脑转移瘤的乳腺转移瘤仅在22%的病例中起源于假血管型。病因发病机制是双重的;它可能是肿瘤细胞阻塞动脉(活跃性肿瘤栓子)的表现,也可能是血管壁破裂和出血的表现。就诊断而言,只有当发现轴外肿瘤,尤其是具有明显轴内嗜性的肿瘤时,这种综合征才能很容易被识别。

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