[Cytobiochemical characteristics of Candida boidinii in continuous culture on methanol and HCO3-].

The cytological and biochemical characteristics of the yeast Candida boidinii KDI were studied under the conditions of continuous cultivation in media containing methanol in the presence of exogenous bicarbonate and without it. Bicarbonate addition was found to cause a decrease in the activity of catalase, a reorganization of the peroxisomes, and an increase in the activity of pyruvate and phosphoenolpyruvate carboxylases, the enzymes involved in heterotrophic assimilation of carbon dioxide.