Haghighi-Rad F, Polin D
Poult Sci. 1981 Oct;60(10):2278-83. doi: 10.3382/ps.0602278.
The relationship of plasma estradiol and progesterone levels to fatty liver-hemorrhagic syndrome (FLHS) was studied with three groups of 9 White Leghorn hens per group. One group was fed ad libitum the other two group were force-fed at 120% and 135% of their own pre-experimental daily feed intake. Force-feeding for 3 weeks produced FLHS. The average FLHS score was 1.6 for control, 3.7 for 120% force-fed, and 4.5 for 135% force-fed. The average liver fat contents were 31.3%, 75.1%, and 76.8% (dry matter basis), respectively. Plasma estradiol averaged 165 pg/ml in the control group and 194 and 247 pg/ml in groups force-fed at 120% and 135%, respectively. The correlation coefficient between plasma estradiol and FLHS was .72 (P less than .01). No significant differences in plasma progesterone were obtained among the control and force-fed groups. The data indicate that high endogenous estrogen levels are associated with FLHS.
采用三组每组9只白来航母鸡，研究了血浆雌二醇和孕酮水平与脂肪肝出血综合征（FLHS）之间的关系。一组自由采食，另外两组分别按其试验前每日采食量的120%和135%进行强制喂食。强制喂食3周诱发了FLHS。对照组的平均FLHS评分为1.6，120%强制喂食组为3.7，135%强制喂食组为4.5。肝脏平均脂肪含量（以干物质计）分别为31.3%、75.1%和76.8%。对照组血浆雌二醇平均为165 pg/ml，120%和135%强制喂食组分别为194和247 pg/ml。血浆雌二醇与FLHS之间的相关系数为0.72（P<0.01）。对照组和强制喂食组之间血浆孕酮无显著差异。数据表明，内源性雌激素水平升高与FLHS有关。
