Locatelli F, Pedrini L, Ponti R, Costanzo R, Di Filippo S, Marai P, Pozzi C, Bonacina G P
Proc Eur Dial Transplant Assoc. 1981;18:146-52.
Forty-three uraemic patients were studied for 60.95 +/- 14.46 months of haemodialytic treatment (4 hours, 3 times/week). After a first dialysis period of 28.95 +/- 14.46 months with a dialysate sodium concentration (NaD) of 142 mEq/L blood pressure (BP) and body weight (BW) showed values significantly lower (p less than 0.001). During a following period of 32 months with NaD 148mEq/L BP did not show significant changes. A more 'physiological' removal of water and sodium by convection does not bring about the feared long term cardiovascular side effects if an appropriate dry BW is achieved, probably because of better correction of the cellular overhydration.
对43例尿毒症患者进行了为期60.95±14.46个月的血液透析治疗(每周3次,每次4小时)。在透析液钠浓度(NaD)为142 mEq/L的首次透析28.95±14.46个月后,血压(BP)和体重(BW)显著降低(p<0.001)。在随后32个月NaD为148 mEq/L的时期,血压没有显著变化。如果能达到合适的干体重,通过对流以更“生理性”的方式清除水和钠不会产生令人担忧的长期心血管副作用,这可能是因为能更好地纠正细胞内水过多的情况。