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超滤与高钠浓度透析:病理生理相关性

Ultrafiltration and high sodium concentration dialysis: pathophysiological correlation.

作者信息

Locatelli F, Costanzo R, Di Filippo S, Pedrini L, Marai P, Pozzi C, Ponti R, Sforzini S, Redaelli B

出版信息

Proc Eur Dial Transplant Assoc. 1978;15:253-9.

PMID:740670
Abstract

Five stabilised uraemic patients underwent two different procedures using the Gambro Ultradiffuser: ultrafiltration alone for one hour (mean body weight loss 2.97 +/- 0.24 kg) and ultrafiltration with simultaneous dialysis for one hour (mean body weight loss 2.92 +/- 0.22 kg) using a given dialysate sodium concentration which reproduced the changes in osmolality which occur during ultrafiltration alone. This mean sodium concentration was 154.75 +/- 2.02 mEq/L. The results did not show significant differences for the two procedures as regards tolerance to dehydration. These results underline the key role of osmolar stability in making dehydration tolerable.

摘要

五名病情稳定的尿毒症患者使用金宝超滤器进行了两种不同的操作

单独超滤一小时(平均体重减轻2.97±0.24千克),以及在使用特定透析液钠浓度的情况下,同时进行超滤和透析一小时(平均体重减轻2.92±0.22千克),该透析液钠浓度再现了单独超滤期间发生的渗透压变化。该平均钠浓度为154.75±2.02毫当量/升。在脱水耐受性方面,两种操作的结果没有显示出显著差异。这些结果强调了渗透压稳定性在使脱水可耐受方面的关键作用。

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