Locatelli F, Costanzo R, Di Filippo S, Pedrini L, Marai P, Pozzi C, Ponti R, Sforzini S, Redaelli B
Proc Eur Dial Transplant Assoc. 1978;15:253-9.
Five stabilised uraemic patients underwent two different procedures using the Gambro Ultradiffuser: ultrafiltration alone for one hour (mean body weight loss 2.97 +/- 0.24 kg) and ultrafiltration with simultaneous dialysis for one hour (mean body weight loss 2.92 +/- 0.22 kg) using a given dialysate sodium concentration which reproduced the changes in osmolality which occur during ultrafiltration alone. This mean sodium concentration was 154.75 +/- 2.02 mEq/L. The results did not show significant differences for the two procedures as regards tolerance to dehydration. These results underline the key role of osmolar stability in making dehydration tolerable.
单独超滤一小时（平均体重减轻2.97±0.24千克），以及在使用特定透析液钠浓度的情况下，同时进行超滤和透析一小时（平均体重减轻2.92±0.22千克），该透析液钠浓度再现了单独超滤期间发生的渗透压变化。该平均钠浓度为154.75±2.02毫当量/升。在脱水耐受性方面，两种操作的结果没有显示出显著差异。这些结果强调了渗透压稳定性在使脱水可耐受方面的关键作用。
