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臭氧暴露对人体肺功能的影响:综述

Effects of ozone exposure on lung function in man: a review.

作者信息

Folinsbee L J

出版信息

Rev Environ Health. 1981;3(3):211-40.

PMID:7330364
Abstract

Ozone, an important component of photochemical smog, has a decided impact on lung function in man. In this review, the effects of zone on human lung function are discussed with particular attention to levels which are near the threshold of producing no effect. Attempts to define dose-response relationships and effects on sensitive subject populations are described. The relationship between exercise and ozone toxicity is presented in addition to the potential impact of ambient ozone exposure on athletic performance. Effects of ozone on respiratory symptoms and the interaction of ozone with other pollutants are briefly examined. Considerable attention has been directed at the phenomenon of adaptation to repeated ozone exposure and to possible mechanism of action of ozone.

摘要

臭氧是光化学烟雾的重要组成部分,对人类肺功能有显著影响。在这篇综述中,将讨论臭氧对人类肺功能的影响,尤其关注接近无效应阈值的浓度水平。文中描述了确定剂量反应关系以及对敏感人群影响的相关尝试。此外,还介绍了运动与臭氧毒性之间的关系,以及环境臭氧暴露对运动表现的潜在影响。简要探讨了臭氧对呼吸道症状的影响以及臭氧与其他污染物的相互作用。人们已相当关注对反复接触臭氧的适应现象以及臭氧可能的作用机制。

相似文献

1
Effects of ozone exposure on lung function in man: a review.臭氧暴露对人体肺功能的影响:综述
Rev Environ Health. 1981;3(3):211-40.
2
Oxidant and acid aerosol exposure in healthy subjects and subjects with asthma. Part II: Effects of sequential sulfuric acid and ozone exposures on the pulmonary function of healthy subjects and subjects with asthma.健康受试者和哮喘患者暴露于氧化剂和酸性气溶胶的情况。第二部分:硫酸和臭氧连续暴露对健康受试者和哮喘患者肺功能的影响。
Res Rep Health Eff Inst. 1994 Nov(70):37-93, discussion 95-112.
3
Effects of ozone on normal and potentially sensitive human subjects. Part II: Airway inflammation and responsiveness to ozone in nonsmokers and smokers.臭氧对正常及潜在敏感人群的影响。第二部分:非吸烟者和吸烟者的气道炎症及对臭氧的反应性
Res Rep Health Eff Inst. 1997 Jun(78):39-72; discussion 81-99.
4
Controlled human studies of ozone exposure.臭氧暴露的人体对照研究。
Scand J Work Environ Health. 1996;22 Suppl 3:52-71.
5
Methods development for epidemiologic investigations of the health effects of prolonged ozone exposure. Part I: Variability of pulmonary function measures.长期臭氧暴露对健康影响的流行病学调查方法发展。第一部分:肺功能测量的变异性
Res Rep Health Eff Inst. 1998 Mar(81):1-25; discussion 109-21.
6
Aldehydes (nonanal and hexanal) in rat and human bronchoalveolar lavage fluid after ozone exposure.臭氧暴露后大鼠和人类支气管肺泡灌洗液中的醛类物质(壬醛和己醛)。
Res Rep Health Eff Inst. 1999 Nov(90):1-15; discussion 17-8.
7
A review of the toxicology of air pollutants: toxicology of chemical mixtures.空气污染物毒理学综述:化学混合物的毒理学
Vet Hum Toxicol. 1996 Oct;38(5):371-7.
8
[Experiences and considerations from 50-year pursuit of ozone effects on man].[五十年来对臭氧对人类影响的探索经验与思考]
Schweiz Rundsch Med Prax. 1992 Mar 10;81(11):328-32.
9
Methods development for epidemiologic investigations of the health effects of prolonged ozone exposure. Part II. An approach to retrospective estimation of lifetime ozone exposure using a questionnaire and ambient monitoring data (California sites).长期臭氧暴露对健康影响的流行病学调查方法开发。第二部分。使用问卷和环境监测数据(加利福尼亚州站点)对终身臭氧暴露进行回顾性估计的方法
Res Rep Health Eff Inst. 1998 Mar(81):27-78; discussion 109-21.
10
Oxidant and acid aerosol exposure in healthy subjects and subjects with asthma. Part I: Effects of oxidants, combined with sulfuric or nitric acid, on the pulmonary function of adolescents with asthma.健康受试者和哮喘患者暴露于氧化剂和酸性气溶胶的情况。第一部分:氧化剂与硫酸或硝酸联合作用对青少年哮喘患者肺功能的影响。
Res Rep Health Eff Inst. 1994 Nov(70):1-36.

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The Effect of Gaseous Ozone Therapy in Conjunction with Periodontal Treatment on Glycated Hemoglobin Level in Subjects with Type 2 Diabetes Mellitus: An Unmasked Randomized Controlled Trial.气态臭氧疗法联合牙周治疗对 2 型糖尿病患者糖化血红蛋白水平的影响:一项非盲随机对照试验。
Int J Environ Res Public Health. 2020 Jul 29;17(15):5467. doi: 10.3390/ijerph17155467.
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Evaluation of the experimental basis for assessment factors to protect individuals with asthma from health effects during short-term exposure to airborne chemicals.评估保护哮喘患者在短期接触空气中化学物质时免受健康影响的评估因素的实验依据。
Crit Rev Toxicol. 2016;46(3):241-60. doi: 10.3109/10408444.2015.1092498. Epub 2015 Oct 29.
3
Daily Oxygen/O₃ Treatment Reduces Muscular Fatigue and Improves Cardiac Performance in Rats Subjected to Prolonged High Intensity Physical Exercise.
每日氧气/臭氧治疗可减轻长时间高强度体育锻炼大鼠的肌肉疲劳并改善心脏功能。
Oxid Med Cell Longev. 2015;2015:190640. doi: 10.1155/2015/190640. Epub 2015 Jul 21.
4
Ozone therapy: A clinical review.臭氧疗法:一项临床综述。
J Nat Sci Biol Med. 2011 Jan;2(1):66-70. doi: 10.4103/0976-9668.82319.
5
Effects of ozone exposure at ambient air pollution episode levels on exercise performance.在环境空气污染事件水平下暴露于臭氧对运动表现的影响。
Sports Med. 1987 Nov-Dec;4(6):395-424. doi: 10.2165/00007256-198704060-00002.
6
[Hypothesis of the changes in the frequency of asthma].[关于哮喘发病率变化的假说]
CMAJ. 1988 Aug 15;139(4):297-304.