Gaultier C, Perret L, Boule M, Buvry A, Girard F
Respir Physiol. 1981 Oct;46(1):71-80. doi: 10.1016/0034-5687(81)90069-4.
The breathing pattern was investigated in 62 children aged 4 to 16 years together with the mouth pressure generated 0.1 s after an occlusion at the endexpiratory level (P0.1). A group of 20 adults (18 to 32 years old) were tested in a similar way. The values of P0.1 obtained during room air breathing at rest in the children decreased with age as a power function P0.1 = 8.51 A-0.62 (where A is age in years), r = -0.74. Adult values of P0.1 were achieved at about 13 years. After O2 inhalation P0.1 decreased in children, but the changes in P0.1 were independent of age. Respiratory frequency decreased with age while inspiratory time (TI) increased, both reaching adult values at about 13 years. The ratio of TI over the total respiratory cycle duration did not change significantly with age in the entire population. The absolute value of tidal volume (VT) increased with age, but not when normalized for body weight (BW). The mean inspiratory flow (VT/TI) normalized for BW decreased with age in children as did P0.1. There was a significant relationship between P0.1 and VT/TI normalized for body weight (r = 0.63).
对62名4至16岁儿童的呼吸模式以及呼气末水平阻塞后0.1秒产生的口腔压力（P0.1）进行了研究。以类似方式测试了一组20名成年人（18至32岁）。儿童在静息状态下室内空气呼吸时获得的P0.1值随年龄增长呈幂函数下降，即P0.1 = 8.51A^-0.62（其中A为年龄，单位：岁），r = -0.74。大约在13岁时达到成人的P0.1值。儿童吸入氧气后P0.1下降，但P0.1的变化与年龄无关。呼吸频率随年龄下降，而吸气时间（TI）增加，两者均在大约13岁时达到成人值。在整个人口中，TI与总呼吸周期持续时间的比值随年龄变化不显著。潮气量（VT）的绝对值随年龄增加，但按体重（BW）标准化后则不然。儿童中按BW标准化的平均吸气流量（VT/TI）随年龄下降，P0.1也是如此。按体重标准化的P0.1与VT/TI之间存在显著关系（r = 0.63）。
