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醋酸环丙孕酮(安鲁米特)诱导晚期前列腺癌显著消退:一例报告

Striking regression of advanced prostatic carcinoma induced by cyproterone acetate (Androcur). A case report.

作者信息

Varenhorst E, Björnlert U, Carlström K

出版信息

Scand J Urol Nephrol. 1981;15(2):157-9. doi: 10.3109/00365598109179594.

DOI:10.3109/00365598109179594
PMID:7330610
Abstract

An 80-year-old man with advanced adenocarcinoma of the prostate received cyproterone acetate, 200 mg orally per day as sole treatment. Striking regression of the tumour was demonstrated by ultrasonograms and excretory urograms. Serum concentrations of acid phosphatases, gonadotrophins, and testosterone decreased significantly. No significant cardiovascular side effects occurred.

摘要

一名80岁晚期前列腺腺癌男性患者,仅接受每天口服200毫克醋酸环丙孕酮的治疗。超声检查和排泄性尿路造影显示肿瘤显著消退。酸性磷酸酶、促性腺激素和睾酮的血清浓度显著下降。未出现明显的心血管副作用。

相似文献

1
Striking regression of advanced prostatic carcinoma induced by cyproterone acetate (Androcur). A case report.醋酸环丙孕酮(安鲁米特)诱导晚期前列腺癌显著消退:一例报告
Scand J Urol Nephrol. 1981;15(2):157-9. doi: 10.3109/00365598109179594.
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The combination of cyproterone acetate and low dose diethylstilbestrol in the treatment of advanced prostatic carcinoma.
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Treatment of prostatic carcinoma with cyproterone acetate.醋酸环丙孕酮治疗前列腺癌
Scand J Urol Nephrol. 1978;12(2):115-8. doi: 10.3109/00365597809179976.
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[Cancers of the prostate and cyproterone acetate. Value of blood testosterone and PSA levels for treatment surveillance].[前列腺癌与醋酸环丙孕酮。血液睾酮和前列腺特异性抗原水平在治疗监测中的价值]
J Urol (Paris). 1990;96(8):431-5.
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Treatment of advanced prostatic cancer with parenteral cyproterone acetate: a phase III randomised trial.醋酸环丙孕酮肠胃外给药治疗晚期前列腺癌:一项III期随机试验
Br J Urol. 1980 Jun;52(3):208-15. doi: 10.1111/j.1464-410x.1980.tb02961.x.
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A morphological study on the effect of cyproterone acetate on human prostatic carcinoma.醋酸环丙孕酮对人前列腺癌作用的形态学研究
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Endocrine effects of cyproterone acetate in patients with prostatic cancer.醋酸环丙孕酮对前列腺癌患者的内分泌影响。
J Urol. 1980 Feb;123(2):180-3. doi: 10.1016/s0022-5347(17)55844-9.
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Orchiectomy combined with cyproterone acetate or prednisone in the treatment of advanced prostatic carcinoma. A randomized clinical and endocrine study.睾丸切除术联合醋酸环丙孕酮或泼尼松治疗晚期前列腺癌。一项随机临床与内分泌研究。
Scand J Urol Nephrol. 1982;16(3):193-7. doi: 10.3109/00365598209179752.
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Palliative effect of cyproterone acetate in carcinoma of the prostate with widespread metastatic bone disease.醋酸环丙孕酮对广泛骨转移前列腺癌的姑息作用。
Br J Urol. 1980 Oct;52(5):402. doi: 10.1111/j.1464-410x.1980.tb03072.x.
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Cyproterone acetate in the treatment of advanced carcinoma of the prostate.醋酸环丙孕酮治疗晚期前列腺癌
J Urol. 1973 Jul;110(1):106-8. doi: 10.1016/s0022-5347(17)60128-9.

引用本文的文献

1
Cyproterone. A review of its pharmacology and therapeutic efficacy in prostate cancer.环丙孕酮。其在前列腺癌中的药理学及治疗效果综述。
Drugs Aging. 1994 Jul;5(1):59-80. doi: 10.2165/00002512-199405010-00006.