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[亚急性硬化性全脑炎(SSPE)的一个非典型病例,(特别提及精神科和心理评估)]

[An atypical case of subacute sclerosing panencephalitis (SSPE), (with special reference to psychiatric and psychological evaluations)].

作者信息

Furlan P M, Riccio A, Quattrocolo G, Sacchi M

出版信息

Minerva Med. 1978 Nov 14;69(55):3795-802.

PMID:733063
Abstract

An atypical case of subacute sclerosing panencephalitis is described, with particular reference to its psychiatric and psychological aspects in the light of the neurological and laboratory data: slow-gamma electrophoresis of the spinal fluid, periodic delta signs in the EEG over about 6 yr, 1/160 blood titre of anti-measles virus antibodies. The history displayed an ingravescent dementia course and the patient's continuing survival for more than 11 yr makes the case the longest recorded in the literature. Both the psychiatric-psychological and neurological symptoms had occurred in distinct stages. It is suggested that neurological recrudescence was responsible for the pattern of symptomatological stabilisation followed by sudden relapses. The symptoms regarded as characteristic of the terminal stage have not yet appeared, especially on the neurological side.

摘要

本文描述了一例亚急性硬化性全脑炎的非典型病例,并根据神经学和实验室数据,特别提及了其精神和心理方面:脑脊液慢γ电泳、脑电图约6年出现周期性δ波、抗麻疹病毒抗体血滴度为1/160。病史显示为进行性痴呆病程,患者持续存活超过11年,使该病例成为文献记载中病程最长的病例。精神心理症状和神经症状均呈不同阶段出现。有观点认为,神经复发是症状稳定后突然复发这一模式的原因。被视为终末期特征的症状尚未出现,尤其是在神经方面。

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