Yamamura K, Maehara N, Harabuchi I, Sadamoto T, Takahashi K, Hayafuji C
Tohoku J Exp Med. 1981 Oct;135(2):179-86. doi: 10.1620/tjem.135.179.
Eight healthy students were exposed to intermittent noise to evaluate the effects of traffic noise on man. The experimental noise exposure conditions were as follows: Exp. 1: Control. Exp. 2: Peak level, 80 dB(A); rise-decay time, 1 sec; duration, 3 sec; and duty cycle 8 sec (on fraction 25%). Exp. 3: Peak level, 75 dB (A); rise-decay time, 500 msec; duration, 4.5 sec; and duty cycle, 8 sec (on fraction 50%). In all experiments, the exposure time was 14 hr. Temporary threshold shift (TTS) growth was followed for 14 hr while saliva cortisol levels were measured for a 24-hr period. Although the coefficient of the regression line of TTS growth recorded in Exp. 1 or Exp. 3 was not statistically significant, the value in Exp. 2 was statistically significant. The circadian rhythm pattern of the saliva cortisol level (during a 24-hr period, mean of 8 examinees) was observed in the three experiments. Essentially, the early morning level of saliva cortisol was high, while the daytime level was relatively low.
八名健康学生暴露于间歇性噪声中,以评估交通噪声对人体的影响。实验噪声暴露条件如下:实验1:对照。实验2:峰值水平,80分贝(A);上升-衰减时间,1秒;持续时间,3秒;占空比8秒(开启比例25%)。实验3:峰值水平,75分贝(A);上升-衰减时间,500毫秒;持续时间,4.5秒;占空比,8秒(开启比例50%)。在所有实验中,暴露时间均为14小时。跟踪临时阈移(TTS)增长14小时,同时在24小时内测量唾液皮质醇水平。虽然实验1或实验3中记录的TTS增长回归线系数无统计学意义,但实验2中的值具有统计学意义。在三个实验中观察了唾液皮质醇水平的昼夜节律模式(24小时内,8名受试者的平均值)。基本上,清晨唾液皮质醇水平较高,而白天水平相对较低。