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尼日利亚北部儿童和成人中的乙型肝炎病毒感染:一项初步调查。

Hepatitis-B virus infection in children and adults in Northern Nigeria: a preliminary survey.

作者信息

Fakunle Y M, Abdurrahman M B, Whittle H C

出版信息

Trans R Soc Trop Med Hyg. 1981;75(5):626-9. doi: 10.1016/0035-9203(81)90133-4.

DOI:10.1016/0035-9203(81)90133-4
PMID:7330917
Abstract

Hepatitis-B surface antigen (HBsAg) and its corresponding antibody (anti-HBs) have been detected by radio-immunoassay in children and adults and in adult expatriates in Zaria, Northern Nigeria. The exposure rate to hepatitis-B virus (frequency of HBsAg and anti-Hbs) was found to vary from 59% in children under five years to 72.5% in adults over 30 years of age, while the frequency of HBsAg alone was 40% and 10% respectively. The anti-HBs prevalence rates rose progressively with age and reached a peak at 62.5% in adults. Five of 32 adult expatriates (15.6%) were positive for anti-HBs. The factors contributing to the high exposure rate in the indigenous population in this region require further study to enable judicious use to be made of preventive measures.

摘要

在尼日利亚北部扎里亚的儿童、成人及成年侨民中,采用放射免疫分析法检测了乙型肝炎表面抗原(HBsAg)及其相应抗体(抗-HBs)。结果发现,乙型肝炎病毒的暴露率(HBsAg和抗-HBs的频率)在5岁以下儿童中为59%,在30岁以上成年人中为72.5%,而仅HBsAg的频率分别为40%和10%。抗-HBs的流行率随年龄增长而逐渐上升,在成年人中达到峰值62.5%。32名成年侨民中有5人(15.6%)抗-HBs呈阳性。该地区本地人群高暴露率的影响因素需要进一步研究,以便合理采取预防措施。

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