Rodríguez Luis J C, Moya M, Domenech E, Méndez A
An Esp Pediatr. 1981 Sep;15(3):258-63.
Fourteen patients diagnosed of neonatal necrotizing enterocolitis (NNE) admitted into the neonatal unit since August 1977 are presented. They were matched to a control group of 130 newborn infants born during that same period of time for sex, weight and gestational age. All patients were formula fed except for three who followed mixed feeding. NNE was closely associated to hypothermia (p less than 0.005), respiratory distress (p less than 0.001) and umbilical catheterization (p less than 0.005). Umbilical catheters introduced for reasons other than distress did not increase the incidence of NNE. Low birth weight infants were more frequently affected than those weighing over 2,500 gm (ratio, 27:1). Evolution was lethal in six cases. The remaining eight are presently under follow up with no evidence of disease.
本文报告了自1977年8月以来收治于新生儿病房的14例诊断为新生儿坏死性小肠结肠炎(NNE)的患儿。将他们与同期出生的130例新生儿对照组在性别、体重和胎龄方面进行匹配。除3例采用混合喂养外,所有患儿均采用配方奶喂养。NNE与体温过低(p<0.005)、呼吸窘迫(p<0.001)及脐血管插管(p<0.005)密切相关。因非窘迫原因插入的脐血管导管并未增加NNE的发病率。低出生体重儿比体重超过2500克的婴儿更易患病(比例为27:1)。6例患儿病情进展至死亡。其余8例目前正在随访中,未发现疾病迹象。