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172例闭合性创伤性脊髓损伤患者损伤区域远端的神经功能恢复情况

Neurological recovery distal to the zone of injury in 172 cases of closed, traumatic spinal cord injury.

作者信息

Young J S, Dexter W R

出版信息

Paraplegia. 1978 May;16(1):39-49. doi: 10.1038/sc.1978.6.

DOI:10.1038/sc.1978.6
PMID:733285
Abstract

The Southwest Regional System for Treatment of Spinal Cord Injury (Good Samaritan Hospital and St Joseph's Hospital, Phoenix, Arizona) treated 325 cases of traumatic spinal cord injury during the period June 1970 through December 1975. Of these, 172 met the study population criteria of the cases reported by Frankel et al. (1969) in their paper 'The value of postural reduction in the initial management of closed injuries of the spine with paraplegia and tetraplegia'. These cases are compared with those reported by Frankel et al. (1969). Cases were divided into neurological categories. The demography of the two study populations was amazingly similar as was the neurological results. The means for the reported neurological changes show that the average recovery for patients treated at Stoke Mandeville was slightly greater for each neurological category; however, this difference was statistically significant only for cervical cases (P less than 0.01). One of the differences in the treatment given by the two centres was that the Southwest Regional System performed surgery on 39% of its cases and Stoke Mandeville none. The Southwest Regional System's non-operated cervical cases showed less average neurological recovery than Stoke Mandeville cervical cases (P less than 0.001). Comparison between the Southwest Regional System non-operated cases and operated cases revealed no significant differences within any neurological category. The average neurological change reported by both centres was relatively small, documenting that from the onset of injury the majority of people sustaining spinal cord injury are committed to living with paralysis, in most cases severe, for the rest of their lives.

摘要

西南地区脊髓损伤治疗系统(位于亚利桑那州凤凰城的撒玛利亚慈善医院和圣约瑟夫医院)在1970年6月至1975年12月期间治疗了325例创伤性脊髓损伤病例。其中,172例符合弗兰克尔等人(1969年)在其论文《体位复位在伴有截瘫和四肢瘫的脊柱闭合性损伤初始治疗中的价值》中报告的病例研究人群标准。将这些病例与弗兰克尔等人(1969年)报告的病例进行比较。病例被分为神经学类别。两个研究人群的数据人口统计学惊人地相似,神经学结果也是如此。报告的神经学变化均值表明,斯托克曼德维尔医院治疗的患者在每个神经学类别中的平均恢复情况略好;然而,这种差异仅在颈椎病例中具有统计学意义(P小于0.01)。两个中心治疗方式的差异之一是,西南地区治疗系统对39%的病例进行了手术,而斯托克曼德维尔医院没有。西南地区未接受手术的颈椎病例的平均神经恢复情况比斯托克曼德维尔医院的颈椎病例差(P小于0.001)。西南地区未接受手术的病例与接受手术的病例之间的比较显示,在任何神经学类别中均无显著差异。两个中心报告的平均神经学变化相对较小,这表明从受伤开始,大多数脊髓损伤患者注定要在余生中带着瘫痪生活,在大多数情况下是严重瘫痪。

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引用本文的文献

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Who is going to walk? A review of the factors influencing walking recovery after spinal cord injury.谁将会行走?脊髓损伤后影响步行恢复因素的综述。
Front Hum Neurosci. 2014 Mar 13;8:141. doi: 10.3389/fnhum.2014.00141. eCollection 2014.
2
Spinal canal restoration by posterior distraction or anterior decompression in thoracolumbar spinal fractures and its influence on neurological outcome.
Eur Spine J. 1994;3(6):318-24. doi: 10.1007/BF02200144.
3
The value of more aggressive management in traumatic paraplegia.
Neurosurg Rev. 1986;9(1-2):141-7. doi: 10.1007/BF01743066.
4
Patterns of cervical spine injury and their associated lesions.颈椎损伤模式及其相关病变。
West J Med. 1987 Oct;147(4):428-31.
5
A prospective study on acute spinal injuries.一项关于急性脊柱损伤的前瞻性研究。
Neurosurg Rev. 1989;12(2):107-13. doi: 10.1007/BF01741481.
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Acute spinal cord trauma: is there more hope in the future?急性脊髓损伤:未来是否有更多希望?
Can Med Assoc J. 1979 Dec 8;121(11):1433-4.
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Current concepts in the immediate management of acute spinal cord injuries.急性脊髓损伤即时处理的当前概念
Can Med Assoc J. 1979 Dec 8;121(11):1453-64.