Kanta J, Novotný J, Pumprla P, Cerná E, Bartos F
Exp Pathol. 1981;20(4):230-2. doi: 10.1016/s0232-1513(81)80027-8.
Open wounds were incised in the dorsal skin of female Wistar rats. Solutions of Salmonella typhosa endotoxin (0.25 micrograms to 25 micrograms/ml saline) were applied 3 times a day on granulation tissue formed in the wounds. 5 days of treatment with the lowest endotoxin concentration resulted in 25% increase of the weight of the tissue, a more than 30% increase of DNA content and a 25% increase of hydroxyproline content in the tissue. Further elevation of these values could be obtained by increasing endotoxin concentration by tenfold or hundredfold but these changes were not very pronounced.
在雌性Wistar大鼠的背部皮肤切开开放性伤口。将伤寒沙门氏菌内毒素溶液（0.25微克至25微克/毫升生理盐水）每天3次涂抹于伤口形成的肉芽组织上。用最低内毒素浓度治疗5天导致组织重量增加25%，组织中DNA含量增加超过30%，羟脯氨酸含量增加25%。通过将内毒素浓度提高十倍或百倍可进一步提高这些数值，但这些变化并不十分显著。
