Perlas L A, Kuizon M D, Tajaon R T, Desnacido J A
Food and Nutrition Research Institute, Department of Science and Technology, Philippines.
Southeast Asian J Trop Med Public Health. 1992 Dec;23(4):691-7.
Iron status of pregnant women at different stages of pregnancy was evaluated by comparing values for hemoglobin (Hb), red cell indices, serum iron (SI), transferrin saturation (TS) and serum ferritin (SF) values with those of a group of non-pregnant women of comparable age and socio-economic status. Mean SF values on the second and third trimesters (9.3 +/- 2.60 ng/ml and 7.1 +/- 2.19 ng/ml) were significantly lower compared to that in the first trimester (22.6 +/- 2.20 ng/ml). These levels were also lower than that found in the non-pregnant controls. The trend was the same for TS. Hemoglobin levels of the pregnant subjects were significantly lower than those of the non-pregnant women. Prevalence of iron deficiency based on SF < 12.0 ng/ml and TS < 16.0% was highest at term and lowest during the first trimester indicating a decrease in iron stores as pregnancy progressed. Sensitivity for each of the iron parameters was computed, and it was found that for the diagnosis of iron deficiency in pregnant women, SF has a greater sensitivity than TS, SI, MCV and MCH.
通过比较血红蛋白（Hb）、红细胞指数、血清铁（SI）、转铁蛋白饱和度（TS）和血清铁蛋白（SF）的值与一组年龄和社会经济地位相当的非孕妇的值，评估了不同孕期孕妇的铁状态。孕中期和孕晚期的平均SF值（9.3±2.60 ng/ml和7.1±2.19 ng/ml）与孕早期（22.6±2.20 ng/ml）相比显著降低。这些水平也低于非孕对照组。TS的趋势相同。孕妇的血红蛋白水平显著低于非孕妇。基于SF<12.0 ng/ml和TS<16.0%的缺铁患病率在足月时最高，在孕早期最低，表明随着孕期进展铁储备减少。计算了每个铁参数的敏感性，发现对于诊断孕妇缺铁，SF比TS、SI、MCV和MCH具有更高的敏感性。
