Nielsen J L, Ellegaard J, Marqversen J, Hansen H H
Scand J Haematol. 1981 Jul;27(1):51-6. doi: 10.1111/j.1600-0609.1981.tb00451.x.
Splenosis or ectopic spleens were detected in 22 of 45 patients splenectomized after either abdominal trauma or accidental lesions of the spleen during operation. The incidence of ectopic spleen tissue in various groups of splenectomized patients has been investigated by a sensitive scanning method employing reinjection of 99mTc-labelled heat damaged autologous erythrocytes. In comparison 7 cases were found among 45 patients who underwent splenectomy for haematological reasons. The time span between the operation and a positive scan varied between 3 months and 11 years. None of the patients in the haematological group with reoccurrence of spleen tissue presented any signs of relapse of their primary disorder. The only patient with overwhelming infection was a girl in whom splenectomy was performed for hereditary spherocytosis. She recovered from the sepsis and her scan was negative. It is concluded that recurrence of spleen tissue is frequent after traumatic lesions of the spleen but rare after selective splenectomy for haematological reasons. This may account for the lesser tendency to overwhelming sepsis after post-traumatic splenectomy.
在45例因腹部外伤或手术中脾脏意外损伤而接受脾切除术的患者中，有22例检测到脾组织植入或异位脾脏。采用再次注射99mTc标记的热损伤自体红细胞的灵敏扫描方法，对各脾切除患者组中异位脾组织的发生率进行了研究。相比之下，在45例因血液系统疾病接受脾切除术的患者中，发现7例有异位脾组织。手术与扫描呈阳性之间的时间间隔为3个月至11年。血液系统疾病组中脾脏组织复发的患者均未出现原发疾病复发的任何迹象。唯一发生暴发性感染的患者是一名因遗传性球形红细胞增多症接受脾切除术的女孩。她从败血症中康复，扫描结果为阴性。结论是，脾脏创伤性损伤后脾脏组织复发很常见，但因血液系统疾病进行选择性脾切除术后则很少见。这可能是创伤后脾切除术后发生暴发性败血症倾向较小的原因。
