Dark J F, Mousalli H, Vaughan R
Thorax. 1981 Dec;36(12):891-5. doi: 10.1136/thx.36.12.891.
Seven hundred and seventy-two patients suffering from carcinoma of the oesophagus and upper stomach were seen by two surgeons at the Manchester Regional Cardiothoracic Centre over a 15-year period. Five hundred and thirty-one patients had an operation, and of these, 449 had a resection. Throughout the period under review, the policy was to resect the primary tumour whenever possible. No emphasis was placed on extensive preoperative parenteral feeding. Adequate rather than radical resection was the aim of the surgery, but even if a curative operation was not possible, the primary was removed if at all possible. Gastric drainage in the immediate postoperative period by nasogastric tube or pyloroplasty was never used. A new classification of high or low tumours according to the level seen at oesophagoscopy is suggested; in 30 cases designated as "high", a planned resection was carried out using a bilateral thoracotomy, a method not previously described. The overall operative mortality was 9.2%. Of those having a resection it was 7.6%, and there were only three deaths in the last 120 resections. The predicted actuarial survival in this series of resections was 18% at five years and 12% at 10 years.
在15年的时间里,曼彻斯特地区心胸中心的两位外科医生诊治了772例食管癌和胃上部癌患者。531例患者接受了手术,其中449例进行了切除手术。在整个审查期间,政策是尽可能切除原发性肿瘤。术前未强调广泛的胃肠外营养。手术的目标是进行充分而非根治性的切除,但即使无法进行根治性手术,也尽可能切除原发性肿瘤。术后从未通过鼻胃管或幽门成形术进行胃引流。建议根据食管镜检查所见水平对肿瘤进行新的高或低分类;在30例被指定为“高位”的病例中,采用双侧开胸手术进行了计划性切除,这是一种此前未描述过的方法。总体手术死亡率为9.2%。接受切除手术的患者死亡率为7.6%,在最后120例切除手术中仅有3例死亡。这一系列切除手术的预计精算生存率在5年时为18%,在10年时为12%。