Olivieri-Sangiacomo C, Del Fà A, Gangitano C
Boll Soc Ital Biol Sper. 1981 Nov 15;57(21):2179-83.
The ultrastructural localization of AChE activity has been investigated in the chick ciliary ganglion during embryonic development. Such activity first appears in a relatively early embryonic stage, i.e. at the 6th day of incubation, in the differentiating cisternae of the rough endoplasmic reticulum. In the period between 10 and 15 days of incubation, the reaction product progressively increases extending to other neuronal areas as Golgi complexes, the perinuclear cisterna and some rare areas of the plasma membrane. In particular a certain amount of AChE appears to occur at the neuronal surface where it is contacted by calyciform synaptic nerve endings. This is conceivably to correlate with the morpho-functional maturation of ganglionic synapses.
在胚胎发育过程中,对鸡睫状神经节中乙酰胆碱酯酶(AChE)活性的超微结构定位进行了研究。这种活性最早出现在相对较早的胚胎阶段,即孵化第6天,在粗面内质网的分化池中。在孵化10至15天期间,反应产物逐渐增加,并扩展到其他神经元区域,如高尔基体复合体、核周池和质膜的一些稀有区域。特别是在神经元表面,当与花萼状突触神经末梢接触时,会出现一定量的AChE。可以想象,这与神经节突触的形态功能成熟有关。