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子宫内膜异位症患者的排卵功能障碍

Ovulatory dysfunction in patients with endometriosis.

作者信息

Badawy S Z, Nusbaum M, Taymour E, Cittadino R, Marshall L

出版信息

Diagn Gynecol Obstet. 1981 Winter;3(4):305-7.

PMID:7338159
Abstract

The incidence of ovulatory dysfunction (anovulation, oligo-ovulation, and luteal phase defect) in 103 patients with endometriosis and infertility was found to be 27.2%. Ovulatory dysfunction was found to occur at a slightly higher age group than the patients with normal ovulatory pattern (p less than 0.02). Prior use of oral steroidal contraceptives does not increase the incidence of ovulatory dysfunction. In addition, there is no correlation between the duration of infertility, and te incidence of ovulatory dysfunction in this group of patients with endometriosis. This report suggests an association between endometriosis and ovulatory dysfunction in some patients, which adds to the etiology of their infertility. It is also suggested that the diagnosis of endometriosis should be suspected in cases of unexplained infertility, even if the pelvic examination does not have any positive objective findings.

摘要

在103例患有子宫内膜异位症和不孕症的患者中,排卵功能障碍(无排卵、稀发排卵和黄体期缺陷)的发生率为27.2%。发现排卵功能障碍发生的年龄组略高于排卵模式正常的患者(p小于0.02)。既往使用口服甾体类避孕药不会增加排卵功能障碍的发生率。此外,在这组子宫内膜异位症患者中,不孕持续时间与排卵功能障碍的发生率之间没有相关性。本报告提示在一些患者中子宫内膜异位症与排卵功能障碍之间存在关联,这增加了其不孕的病因。还建议在不明原因不孕的病例中,即使盆腔检查没有任何阳性客观发现,也应怀疑子宫内膜异位症的诊断。

相似文献

1
Ovulatory dysfunction in patients with endometriosis.子宫内膜异位症患者的排卵功能障碍
Diagn Gynecol Obstet. 1981 Winter;3(4):305-7.
2
Characteristics of infertile patients with ovulatory dysfunction and their relation to body mass index.排卵功能障碍不孕患者的特征及其与体重指数的关系。
J Ayub Med Coll Abbottabad. 2009 Jul-Sep;21(3):12-6.
3
Ovulatory dysfunction and endometriosis.排卵功能障碍与子宫内膜异位症。
Prog Clin Biol Res. 1982;112 Pt B:195-200.
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Clinical presentation and diagnosis of endometriosis.子宫内膜异位症的临床表现与诊断
Obstet Gynecol Clin North Am. 1989 Mar;16(1):29-42.
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New aspects of the pathophysiology of endometriosis and associated infertility.子宫内膜异位症的病理生理学及相关不孕症的新进展。
J Reprod Med. 1980 Jun;24(6):257-60.
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Occult ovulatory dysfunction in women with minimal endometriosis or unexplained infertility.轻度子宫内膜异位症或不明原因不孕症女性的隐匿性排卵功能障碍。
Fertil Steril. 1988 Nov;50(5):716-20.
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Exogenous gonadotropin therapy in World Health Organization groups I and II ovulatory disorders.世界卫生组织I型和II型排卵障碍的外源性促性腺激素治疗
Obstet Gynecol. 1994 Feb;83(2):189-96.
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Letrozole vs. clomiphene citrate in patients with ovulatory infertility.来曲唑与枸橼酸氯米芬治疗排卵性不孕症患者的对比研究
Fertil Steril. 2006 Apr;85(4):1045-8. doi: 10.1016/j.fertnstert.2005.09.045. Epub 2006 Mar 9.
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The current status of infertility associated with pelvic endometriosis.盆腔子宫内膜异位症相关不孕症的现状
Clin Reprod Fertil. 1983 Jun;2(2):97-112.
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A prospective study of infertility due to ovulatory disorders, ovulation induction, and incidence of breast cancer.一项关于排卵障碍所致不孕症、促排卵及乳腺癌发病率的前瞻性研究。
Arch Intern Med. 2006;166(22):2484-9. doi: 10.1001/archinte.166.22.2484.

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