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新生期用6-羟基多巴胺处理的成年大鼠的选择性注意功能障碍

Selective attention dysfunctions in adult rats neonatally treated with 6-hydoxydopamine.

作者信息

Oke A F, Adams R N

出版信息

Pharmacol Biochem Behav. 1978 Oct;9(4):429-32. doi: 10.1016/0091-3057(78)90036-9.

DOI:10.1016/0091-3057(78)90036-9
PMID:733830
Abstract

Adult rats treated intracisternally with 6-hydroxydopamine during the perinatal period were trained on a black-white discrimination. Alterations in cue shape and cue location failed to selectively distinguish differences in response patterns for the treated animals. However, when irrelevant stimuli were added to the discriminative array, the 6-hydroxydopamine group evidenced marked impairment of performance throughout the period of distraction.

摘要

在围产期经脑池内注射6-羟基多巴胺处理的成年大鼠接受了黑白辨别训练。线索形状和线索位置的改变未能选择性地区分经处理动物的反应模式差异。然而,当无关刺激添加到辨别阵列中时,6-羟基多巴胺组在整个干扰期均表现出明显的行为表现受损。

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[Adaptation to the behavioral effects of 6-hydroxydopamine].[对6-羟基多巴胺行为效应的适应性]
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