Schöpper C, Robenek H, Fasske E, Fetting R, Themann H
J Cancer Res Clin Oncol. 1981;102(2):159-67. doi: 10.1007/BF00410667.
In this study a transplantable sebaceous adenoma is presented, which maintained its histological structure with similarities to normal sebaceous glands over a long series of transplantations. From the periphery toward the center a basal lamina, an outer layer of undifferenciated stem cells, loosely connected secreting tissue, a tightly packed zone of close cell attachment, and finally a central sebaceous zone can be distinguished. Special reference is made to the belt-like region around the zone of cell lysis and sebum accumulation, which forms a barrier to the surrounding tissue by means of numerous cell adhesions in the form of desmosomes. Relatively few virus particles of the retrovirus group, particularly type A particles, were found in any of the examined tumors.
在本研究中，我们展示了一种可移植的皮脂腺腺瘤，在一系列长时间的移植过程中，它保持了与正常皮脂腺相似的组织结构。从周边向中心，可以区分出基膜、未分化干细胞外层、松散连接的分泌组织、紧密细胞附着的紧密堆积区，以及最后的中央皮脂腺区。特别提及细胞溶解和皮脂积累区域周围的带状区域，该区域通过桥粒形式的大量细胞粘附形成对周围组织的屏障。在任何一个检查的肿瘤中，发现逆转录病毒组的病毒颗粒相对较少，尤其是A型颗粒。
