Apple D J, Gieser D K, Goldberg M F
Klin Monbl Augenheilkd. 1981 Nov;179(5):336-9. doi: 10.1055/s-2008-1057324.
Light and electron-microscopic analysis of the enucleated eye of a 55-year-old man confirmed the diagnosis of Coats' syndrome. The histopathologic findings in this adult patient are identical to those seen in typical cases of Coats' syndrome of childhood. The characteristic thickening of vessel walls and the apparent deficiency of healthy, viable retinal vascular endothelial cells support the hypothesis that the ocular changes in this syndrome are directly related to a primary retinal vascular defect leading to abnormal permeability.
对一名55岁男性摘除眼球的光镜和电镜分析证实了科茨综合征的诊断。该成年患者的组织病理学发现与儿童期典型科茨综合征病例所见相同。血管壁的特征性增厚以及健康、有活力的视网膜血管内皮细胞明显缺乏，支持了该综合征眼部变化与导致通透性异常的原发性视网膜血管缺陷直接相关的假说。
